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Smoked Brisket Grilled Cheese

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Smoky, cheesy, and dripping with BBQ flavor—this Smoked Brisket Grilled Cheese is a comfort food masterpiece. Piled high with tender brisket, melty cheese, and a golden, buttery crust, it’s the sandwich that turns leftovers into a next-level meal.

Ingredients

Scale

8 slices thick-cut bread

Salted butter, room temperature

½ tsp Italian seasoning

¼ tsp garlic powder

4 oz Gruyère cheese, grated

4 oz sharp cheddar cheese, grated (like Cabot Seriously Sharp)

4 oz Monterey Jack cheese, grated (like Cabot Monterey Jack)

12 oz smoked beef brisket, chopped (~2 cups)

4 tbsp barbecue sauce

Instructions

Season the Butter: Mix softened butter with Italian seasoning and garlic powder. Spread on one side of each bread slice.

Prep the Filling: Toss chopped brisket with barbecue sauce.

Assemble the Sandwiches: On the unbuttered side of a bread slice, layer a mix of cheeses, a generous scoop of brisket, and more cheese. Top with another bread slice, buttered side out.

Grill It: Heat a skillet over medium heat. Cook each sandwich 3–4 minutes per side, until golden and the cheese is melted.

Serve Hot: Let sit briefly before slicing—so the cheese stays perfectly gooey.

Nutrition

Find it online: https://thecomfortspoon.com/smoked-brisket-grilled-cheese/